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作者报告3例发生于皮肤纤维瘤基础上的色素沉着结节性基底细胞癌和19例基底细胞癌样变。这3例色素沉着结节性基底细胞癌患者一男二女,其年龄是40、44、46岁,损害大小为10×13毫米至1.4厘米,病期较长可达10年之久,临床诊断为恶性黑色素瘤、血管瘤及痣等。在切除后活检发现为硬化性血管瘤型皮肤纤维瘤、硬化性血管瘤及皮肤纤维瘤,在此基础上均能见到数个境界整齐的,由圆形或卵圆形嗜碱性细胞组成的岛屿状结构,其边缘有栅状细胞排列与附近真皮隔开或与表皮相连,有的边缘皱缩出现空隙,岛屿状肿瘤中有色素堆积。以上3例是结节性基底钿胞癌位于皮肤纤维瘤上。
The authors report 3 cases of pigmented nodular basal cell carcinoma based on dermatofibroma and 19 cases of basal cell carcinoma. The three patients with pigmented nodular basal cell carcinoma were one male and two females, whose ages were 40, 44, 46 years old, and the lesion size was 10 x 13 mm to 1.4 cm. The disease duration was as long as 10 years. Clinical diagnosis For malignant melanoma, hemangiomas, and warts. After excision, biopsy revealed sclerosing hemangiomas, sclerosing hemangiomas, and dermatofibromas. On this basis, several neat circles can be seen, consisting of round or oval basophils. The island-like structure has a palisade cell arrangement at the periphery that is separated from the adjacent dermis or connected with the epidermis, and some of the edges are creased with gaps, and pigments accumulate in the island-like tumors. In the above 3 cases, nodular basal cell carcinoma was located on dermal fibroids.