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目的:观察中西医结合治疗对多囊卵巢综合征(PCOS)合并胰岛素抵抗(IR)患者内分泌的影响。方法:将128例患者随机分为治疗组和对照各64例,2组患者均口服达因-35、二甲双胍片;治疗组根据月经周期加用黄体期方、卵泡期方中药治疗,疗程均为3个月经周期。结果:治疗后2组患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白蛋固醇(LDL-C)、空腹胰岛素(FINS)、糖负荷后1h胰岛素(1hINS)、糖负荷后2h胰岛素(2hINS)均较治疗前有明显下降(P<0.05),促卵泡生成素(FSH)明显升高(P<0.05);且治疗组上述指标改善较对照组显著(P<0.05)。结论:中西医结合治疗对调节PCOS伴IR患者的内分泌紊乱疗效显著,效果优于单纯西药治疗。
Objective: To observe the effect of integrated traditional Chinese and western medicine on endocrine in patients with polycystic ovary syndrome (PCOS) and insulin resistance (IR). Methods: 128 patients were randomly divided into treatment group and control group of 64 cases, two groups of patients were oral darin -35, metformin tablets; treatment group according to the menstrual cycle plus luteal phase, follicular phase of traditional Chinese medicine treatment, treatment were 3 menstrual cycle. Results: The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), fasting insulin (FINS), insulin 1hINS after sugar loading (P <0.05), and follicle-stimulating hormone (FSH) was significantly increased (P <0.05). The improvement of the above indexes in the treatment group was more significant than that in the control group (P <0.05) . Conclusion: Integrative treatment of PCOS with IR patients with endocrine disorders significant effect, the effect is better than Western medicine alone.