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目的分析不同剂量纳洛酮用于治疗新生儿窒息的效果。方法随机选择2015年1月至2016年1月在本院接受治疗的窒息新生儿60例参与研究,随机平均分成2组,对照组利用小剂量纳洛酮对患儿进行治疗,观察组利用大剂量纳洛酮对患儿进行治疗,比较两组效果。结果对照组组呼吸、心率、皮肤颜色、原始反射、肌张力恢复时间分别为(9.45±3.56)min、(7.38±2.24)min、(8.28±2.53)min、(72.15±39.14)min、(98.46±72.15)min,观察组分别为(4.15±3.44)min、(2.64±1.82)min、(3.76±1.31)min、(40.13±36.14)min、(62.14±48.72)min(P<0.05);两组不良反应发生情况比较没有统计学意义(P>0.05)。结论大剂量纳洛酮治疗新生儿窒息效果要优于小剂量,治疗安全性高,值得推广。
Objective To analyze the effect of different doses of naloxone on the treatment of neonatal asphyxia. Methods A total of 60 neonates with asphyxia treated in our hospital from January 2015 to January 2016 were randomly divided into two groups. The control group was treated with low-dose naloxone, and the control group was treated with large Dose Naloxone treatment of children, the two groups were compared. Results The recovery time of respiration, heart rate, skin color, original reflex and muscle tone in control group were (9.45 ± 3.56) min, (7.38 ± 2.24) min, (8.28 ± 2.53) min and ± 2.72 ± 1.31) min, (40.13 ± 36.14) min and (62.14 ± 48.72) min respectively in the observation group (P <0.05) The occurrence of adverse reactions in the group was not statistically significant (P> 0.05). Conclusion High-dose naloxone is better than low-dose in the treatment of neonatal asphyxia, and it is safe to treat and worth popularizing.