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本文通过对１８０例肺心病人血液流变学、超氧化物岐化酶及血气、酸碱的检测。结果发现，急性发作期，缓解期血清中ＳＯＤ—１活性均明显高于正常对照组（Ｐ＜０．０１）。本研究提示（１）氧自由基可能参与了肺心病的病理、生理过程。（２）慢性肺心病急性发作期血清、全血ＳＯＤ－１的含量高低对于诊断病情和估计预后具有重要意义。（３）为ＳＯＤ－１作为肺心病的一种外源性的治疗药物提供了依据，可能对于减轻肺损伤，减少及预防并发症的发生，促进肺心病的逆转、提高治愈率、降低死亡率具有十分重要的意义。
In this paper, 180 cases of pulmonary heart disease patients with hemorheology, superoxide dismutase and blood gas, acid and alkali detection. The results showed that in acute exacerbation, serum SOD-1 activity were significantly higher than the normal control group (P <0.01). The study suggests (1) oxygen free radicals may be involved in the pathophysiology of pulmonary heart disease. (2) The level of serum and whole blood SOD-1 in acute episodes of chronic pulmonary heart disease is of great significance for the diagnosis of the disease and prognosis. (3) It provides a basis for SOD-1 as an exogenous therapeutic drug for pulmonary heart disease, which may reduce lung injury, reduce and prevent complications, promote the reversal of pulmonary heart disease, improve the cure rate and reduce the mortality rate It is of great significance.