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目的:观察以大量补液为主的非透析疗法对急性肾前性肾功能衰竭的疗效。方法:将30例急性肾前性肾功能衰竭的患者随机分为观察组和对照组各15例。观察组在常规治疗的基础上予大量补液,每天补液量5000～10000 ml,对照组每天补液控制在2000 ml以内。观察两组间治疗前后的症状、尿量、肌酐、尿素氮的变化。结果:观察组显效6例,好转6例,无效3例转入血透治疗,有效率80%。而对照组中显效为0,好转5例,无效10例,有效率33%。两组比较有显著差异,P<0.05。结论:大量补液可以增加肾血流量,改善肾脏的有效灌注,有利肾小管功能的恢复,对急性肾前性肾功能衰竭有良好的疗效。
OBJECTIVE: To observe the effect of non-dialysis therapy mainly on pleural effusion in patients with acute prerenal renal failure. Methods: Thirty patients with acute prerenal renal failure were randomly divided into observation group and control group, 15 cases each. The observation group was given a large amount of fluid rehydration on the basis of routine treatment, the volume of fluid per day was 5000-10000 ml, and the control group was controlled within 2000 ml per day. The changes of symptoms, urine output, creatinine and urea nitrogen between the two groups before and after treatment were observed. Results: The observation group was significantly improved in 6 cases, improved in 6 cases, 3 cases were ineffective hemodialysis treatment, the effective rate was 80%. The control group was markedly effective in 0, improved in 5 cases, ineffective in 10 cases, effective rate of 33%. There was a significant difference between the two groups, P <0.05. Conclusion: A large amount of rehydration can increase renal blood flow, improve the effective perfusion of the kidneys, facilitate the recovery of renal tubule function, and have a good curative effect on acute prerenal renal failure.