论文部分内容阅读
桂枝汤有效部位Ａ（Ｆｒ．Ａ）对酵母致热大鼠下丘脑三磷酸肌醇（ＩＰ３）和钙调蛋白（ＣａＭ）的降低及安痛定诱致低体温大鼠下丘脑ＩＰ３和ＣａＭ含量的升高均有明显的逆转效应，即使高体温大鼠下丘脑ＩＰ３和ＣａＭ升高，低体温大鼠ＩＰ３和ＣａＭ降低，分别使之趋向正常。结果提示，Ｆｒ．Ａ对体温的双向调节有中枢神经细胞内信息传递系统ＩＰ３和ＣａＭ参予。
Effect of Fraction A (Fr. A) on Hypothalamic Inositol Trisphosphate Inositol (IP3) and Calmodulin (CaM) in Yeast-Induced Rats and Hypothalamus IP3 and CaM Content in Hypothermia Rats Induced by Antongding The elevations have a significant reversal effect. Even though IP3 and CaM in the hypothalamus increase in hyperthermia rats, IP3 and CaM decrease in hypothermia rats, respectively, making them tend to be normal. The results suggest that Fr. A two-way regulation of body temperature has central nervous cell intracellular signaling systems IP3 and CaM.