一、胰腺炎与磷脂酶A 的关系磷脂酶A(phospholipase A,PA)广泛存在于人、鼠、荷兰鼠、牛、马、猪、羊、蛇及蜂等动物体内。在人体,它以不活化的酶前身形式主要分布于胰腺,随胰液分泌入十二指肠。近年来,PA 日益引起人们的关注,其一部分原因是与胰腺炎研究的进展分不开的。早在1868年,德国医生Klebs 认为胰蛋白酶能引起胰腺感染。1874年,Zenker 将胰腺感染称为急性胰腺炎,并报道胰腺炎可引起患者猝死,死因与胰腺出血有关。1875年, First, the relationship between pancreatitis and phospholipase A phospholipase A (PA) is widely present in animals such as humans, rats, dutch rats, cattle, horses, pigs, sheep, snakes and bees. In the human body, it is mainly distributed in the pancreas in the form of an inactive precursor of the enzyme and secreted into the duodenum with pancreatic juice. In recent years, PA has aroused people’s attention more and more, partly due to the progress of pancreatitis research inseparable. As early as 1868, German doctor Klebs thought that trypsin can cause pancreas infection. In 1874 Zenker called pancreas infection acute pancreatitis and reported that pancreatitis causes sudden death in patients with pancreatic bleeding. In 1875,