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目的了解小儿肺炎支原体肺炎的感染状况及肺外表现的特点。方法对2 332例肺炎支原体肺炎住院患儿取静脉血,采用ELISA方法检测肺炎支原体特异性抗体Ig M(MP-Ig M)。结果检测结果为MP-Ig M阳性例数418例,阳性率为17.92%。其中有肺外表现的116例(27.75%),<1岁22例,~3岁49例,~7岁30例,>7岁15例;男67例,发生率为4.58%(67/1 462),女49例,发生率为5.63%(49/870),不同性别发生率差异无统计学意义(P>0.05);发生率以<1岁小儿最多为42.31%(22/52),肺外器官损害以消化系统表现最多,为39例,其次是血液系统和心血管系统,各为26例和25例。结论肺炎支原体是原发性非典型肺炎的重要病原体之一,感染后除有肺部受损症状外,可有其他多器官、多系统受累表现,常给临床诊治带来困扰。
Objective To understand the infection of children with Mycoplasma pneumoniae pneumonia and the characteristics of extrapulmonary manifestations. Methods Blood samples were collected from 2 332 inpatients with Mycoplasma pneumoniae pneumonia and the Mycoplasma pneumoniae specific IgM (MP-Ig M) was detected by ELISA. Results The results showed that the number of MP-Ig M positive cases was 418 cases, the positive rate was 17.92%. There were 116 cases (27.75%) with extrapulmonary manifestations, 22 cases <1 year old, 49 cases aged 3 years, 30 cases ~ 7 years old and 15 cases> 7 years old. There were 67 males, the incidence was 4.58% (67/1 462) and 49 women (5.63%, 49/870 respectively). There was no significant difference in the incidence of different genders (P> 0.05). The incidence rate was 42.31% (22/52) in children <1 year old, External organ damage to the digestive system showed the most, 39 cases, followed by the blood system and cardiovascular system, each of 26 cases and 25 cases. Conclusions Mycoplasma pneumoniae is one of the important pathogens of SARS. In addition to the symptoms of lung damage after infection, there may be other multi-organ and multi-system involvement, which often brings trouble to clinical diagnosis and treatment.