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研究观察了生姜提取物姜总酮（ＴｏｔａｌＫｅｔｏｎｅｏｆＧｉｎｇｅｒ，ＴＫＧ）对大鼠颈动脉血栓和小鼠肺血栓形成的影响及急性毒性实验。结果用ＴＫＧ（１０，２０ｍｇ／ｋｇ）可使大鼠颈动脉血流阻塞时间（ＯＴ）明显延长，ＴＫＧ（２０，４０ｍｇ／ｋｇ）可使胶原和肾上腺素形成的诱导剂所致小鼠病死率明显减少，腹腔注射ＴＫＧ的ＬＤ５０及９５％可信限为：５５７．０４ｍｇ／ｋｇ（４３０．９４～７２０．０４ｍｇ／ｋｇ），结果提示ＴＫＧ有较强的抑制血栓形成作用
The effects of ginger extract Total TK (TKG) on the thrombosis of rat carotid artery and pulmonary thrombus in mice and the acute toxicity test were studied. Results TKG (10, 20mg / kg) significantly prolonged the carotid artery occlusion time (OT). TKG (20,40mg / kg) could induce the mice mortality induced by collagen and epinephrine Significantly reduce the LD50 and 95% confidence interval of intraperitoneal injection of TKG: 557.04mg / kg (430.94 ~ 720.04mg / kg), the results suggest that TKG has a stronger inhibitory effect on thrombosis