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目的：探讨单磷酸阿糖腺苷联合泛昔洛韦治疗带状疱疹的临床疗效。方法将入选的106例带状疱疹患者随机分为两组，治疗组：予单磷酸阿糖腺苷5mg/(kg–d)静滴，同时予泛昔洛韦250mg口服，3次/d；对照组：予泛昔洛韦分散片250mg口服，3次/d；同时两组患者均予口服维生素B1片10mg，3次/d，局部皮损再予以半导体激光照射，1次/d,疗程均为7~14天。结果治疗组总有效率高于对照组，差异有统计学意义（p＜0.05）。治疗组患者止痛、止疱、结痂及痊愈时间、后遗神经痛发生率均优于对照组，差异有统计学意义（p均＜0.05）。结论采用单磷酸阿糖腺苷联合泛昔洛韦治疗带状疱疹起效迅速，疗效显著，明显减少后遗神经痛发生可能，值得在临床大力推广使用。“,”Objective To discuss the clinical treatment effect of vidarabine monophosphate combined with famciclovir in the treatment of patients with herpes zoster(GZ). Methods One hundred and six cases of GZ were randomly divided into 2 groups.Vidarabine monophosphate combined with famciclovir group was supplied with Vidarabine monophosphate 5mg/(kg–d) iv and famciclovir tablets 250mg thrice a day, and famciclovir group as the control, treated with famciclovir tablets 250mg thrice a day. Meanwhile, VitaminB1 tablets 10mg were given oraly thrice a day and local diode laser irradiation once per day in both groups. The therapeutic course for both groups was 7 to 14 days. Results The total effective rate of the Vidarabine monophosphate combined with famciclovir group was higher than that of the controlgroup,the difference was statisticaly significant(p<0.05).The pain aleviation,blister recession,incrustation,cure and incidence of neuralgia of patients in the vidarabine monophosphate combined with famciclovir group were better than those in the control group,the difference was statisticaly significant(p<0.05).Conclusion Using vidarabine monophosphate combined with famciclovir in the treatment of patients with herpes zoster has rapid onset,significant curative effect, and reduces the incidence of neuralgia, and it is worthy of popularizing in clinical use.