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本研究观察了亚硒酸钠对高胆固醇饮食造成鹌鹑动脉粥样硬化消退的影响。结果表明,硒使动物血清总胆固醇,甘油三酯和脂质过氧化物持续显著降低,并明显提高高密度脂蛋白胆固醇/总胆固醇比值。实验15周末动物动脉组织胆固醇含量降低,动脉粥样硬化指数显著减少。提示,硒有明显加速实验性动脉粥样硬化症消退的作用。
This study examined the effect of sodium selenite on regression of atherosclerosis in quail caused by a high cholesterol diet. The results showed that selenium continuously and significantly reduced serum total cholesterol, triglycerides and lipid peroxides and significantly increased the ratio of HDL-C to total cholesterol. During the experiment 15 weeks, the arterial tissue cholesterol content decreased and atherosclerosis index decreased significantly. Tip, selenium significantly accelerated experimental atherosclerosis subsided role.