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目的 报告 47例小儿肛门漏油症病例 ,并分析其临床资料 ,归纳临床表现 ,制订诊断标准及治疗方案。方法 凡符合诊断标准 (肛门不自主油脂溢出 ;精神、食欲正常 ,无腹痛、腹泻及便秘等症状 ,除肛门周围有油脂污染无其他异常体征者 ;大便外观成形 ,次数未增加和 /或成形便表面可见油脂物 ;粪便涂片检查脂肪球阳性 ,无其他异常成分 ;未曾服用减肥药 )之患儿均纳入本观察组。并均予以多酶片 (每片含胰脂肪 2 0 0U、胰蛋白酶 16 0U、胃蛋白酶 48U、胰淀粉酶 190 0U)治疗 ,每次 1～ 2片 ,每日 3次 ,连续服用 10日为 1个疗程。结果 本组 47例 ,男 40例、女 7例 ,男∶女 =5 7∶1。 47例均小于 10岁 ,其中 1～ 3岁 17例占 36 18% ;～ 6岁 15例占 31 91% ;～ 10岁 15例占 31 91%。病程 2天～ 8个月 ,其中 <7天 2 0例占 42 5 5 % ;8～ 14天 5例占 10 6 4% ;15～ 2 1天 5例占 10 6 4% ;>2 1天 17例占 36 17%。服用多酶片后显效 30例占 6 3 83% ;有效 10例占 2 1 2 8% ;失访 7例占 14 89%。结论 小儿肛门漏油症临床表现独特 ,病因不明 ,多酶片口服治疗有效。
Objective To report 47 cases of pediatric anal leakage and analyze their clinical data, summarize the clinical manifestations, formulate diagnostic criteria and treatment plan. Methods All patients who met the diagnostic criteria (anal involuntary fat spill; mental, normal appetite, no abdominal pain, diarrhea and constipation, except those with other abnormal signs of oil pollution around the anus, stool appearance, no increase in frequency, and / The surface of the visible lipid; stool smears positive fat globules, no other abnormalities; never taking diet pills) were included in this observation group. And were given to the multi-enzyme tablets (each containing pancreatic fat 200UU, trypsin 16 0U, pepsin 48U, pancreatic amylase 190 0U) treatment, each 1 to 2 tablets 3 times daily for 10 days 1 course of treatment. Results The group of 47 cases, 40 males and 7 females, male: female = 5 7: 1. 47 cases were less than 10 years old, of which 17 cases of 1 to 3 years accounted for 36 18%; 15 cases of 6 years accounted for 31 91%; ~ 10 years old 15 cases accounted for 31 91%. The course of disease ranged from 2 days to 8 months, of which 20 cases accounted for 42 5 5% within 7 days, 10 6 4 cases from 8 to 14 days, 10 6 4% from 15 to 21 days and 21 days 17 cases accounted for 36 17%. After taking multi-enzyme tablets, 30 cases accounted for 6 3 83%; 10 cases accounted for 2 1 2 8%; and 7 cases lost 14 89%. Conclusion The clinical manifestations of pediatric anal leakage are unique and the etiology is unknown. Multi-enzyme tablets are effective in oral administration.