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目的观察探讨降钙素原在评价急性胰腺炎预后的临床应用方法及效果,总结其临床意义。方法选取我院2011年7月至2012年7月33例急性胰腺炎的患者,按照其病情严重程度分为A组(急性水肿型,MAP组)21例,B组(急性出血坏死型,SAP组)12例,观察对两组患者在入院时和入院后48h进行血清中的PCT、CRP水平进行检测,然后采取APACHEⅡ评分标准进行评分,观察比较两组检测结果,并观察检测指标与预后间的关系。结果两组患者在入院后的PCT、CRP水平和APACHEⅡ评分比较,明显高于住院时的值,差异有统计学意义(P<0.05),具有统计学意义;而入院48h后,B组的升高程度显著高于A组(P<0.05),具有统计学意义。结论入院后48h进行血清中的PCT、CRP水平进行检测能够有助于评价患者的病情严重程度,监测病情进展及评估预后,具有重要的临床意义。
Objective To investigate the clinical application of procalcitonin in evaluating the prognosis of acute pancreatitis and to summarize its clinical significance. Methods A total of 33 acute pancreatitis patients from July 2011 to July 2012 in our hospital were divided into group A (acute edema type, MAP group) and group B (acute hemorrhagic necrosis type, SAP Group) 12 cases were observed in the two groups of patients at admission and 48h after admission serum PCT, CRP levels were detected, and then take the APACHE Ⅱ score standard score, observed and compared the results of two groups, and observed between the detection index and prognosis Relationship. Results The PCT, CRP levels and APACHEⅡ scores after admission in the two groups were significantly higher than those in hospital, with statistical significance (P <0.05), which were statistically significant. After 48h admission, High level was significantly higher than the A group (P <0.05), with statistical significance. Conclusion It is of great clinical significance to detect the level of PCT and CRP in serum at 48h after admission for evaluating the severity of the disease, monitoring the progression of the disease and assessing the prognosis.