微囊性附属器癌(MAC)又称为硬化性汗腺导管癌及汗管瘤样癌,是一种具有向毛囊和汗腺双向分化、局部浸润性生长和硬化性间质的低度恶性肿瘤。本病组织病理可见较多角质囊肿、管状和腺样结构,基底样细胞条索同时存在,肿瘤细胞常侵袭神经周围及骨骼肌。1982年由Goldstein等[1]首先报告,好发于成年人的头、颈部皮肤,多见于面部、头皮和眼眶周 Microencapsulated adnexal carcinoma (MAC), also referred to as sclerosing ductal adenocarcinoma and synctal carcinoma-like carcinoma, is a low-grade malignancy with bi-directional, locally infiltrative, and sclerosing interstitial involvement of hair follicles and sweat glands. Histopathology of the disease seen more keratinized cysts, tubular and adenoid-like structure, basal-like cell lines exist simultaneously, the tumor cells often affect the nerves around and skeletal muscle. 1982 first reported by Goldstein et al [1], occurs in adults head and neck skin, more common in the face, scalp and orbit