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目的对结直肠癌患者实施治疗过程中奥沙利铂联合卡培他滨化疗的不良反应以及护理措施进行分析。方法结直肠癌患者88例,患者均采用奥沙利铂联合卡培他滨辅助化疗,分析患者的不良反应,并给予相应的护理。结果所有患者均出现不同程度的不良反应症状,主要的不良反应为神经毒性(61.4%)、恶心呕吐(80.7%)、腹泻(30.7%)、骨髓抑制(11.4%)和手足综合征(6.8%)。经过护理后所有患者完成化疗。结论在对结直肠癌患者应用奥沙利铂联合卡培他滨化疗过程中,患者会出现不同程度的不良反应,给患者带来痛苦,影响化疗的顺利完成,因此,应用有效的护理措施,可以预防或减轻患者不良反应发生情况,提高患者化疗中的生活质量,具有重要临床意义。
Objective To analyze the adverse reactions of oxaliplatin combined with capecitabine chemotherapy in the treatment of patients with colorectal cancer and the nursing measures. Methods 88 cases of colorectal cancer patients, patients were treated with oxaliplatin combined with capecitabine adjuvant chemotherapy, analysis of adverse reactions in patients, and give the appropriate care. Results All patients showed different degrees of adverse reactions. The main adverse reactions were neurotoxicity (61.4%), nausea and vomiting (80.7%), diarrhea (30.7%), myelosuppression (11.4%) and hand-foot syndrome ). After treatment, all patients completed chemotherapy. Conclusion In patients with colorectal cancer with oxaliplatin combined with capecitabine chemotherapy, patients will have different degrees of adverse reactions, patients with pain and affect the successful completion of chemotherapy, therefore, the application of effective nursing interventions, Can prevent or reduce the occurrence of adverse reactions in patients with chemotherapy to improve the quality of life in patients with an important clinical significance.