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背景和目的 英国血液HBV、HCV及HIV的感染率非常低,难以采用一般的观测方法加以监视。计算感染率对于血液的安全性控制以及降低输血传播感染风险的宏观策略等方面均具价值。材料和方法调查1993—2001年间,英国献血者中乙型肝炎表面抗原(HBsAg),HCV抗体及HIV抗体的发生和流行率,结合当前检测分析这些标志物方法的‘窗口期’长短以及具
Background and Objective The prevalence of HBV, HCV and HIV infection in the UK is very low and it is difficult to monitor using the general observation methods. Computed infection rates are valuable for controlling the safety of blood and for macro strategies to reduce the risk of transfusion-transmitted infections. MATERIALS AND METHODS The incidence and prevalence of hepatitis B surface antigen (HBsAg), HCV antibodies and HIV antibodies in British blood donors between 1993 and 2001 were investigated in combination with the ’window’ length of the currently assayed methods for detecting these markers