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近几年来药理学文献出现了许多根据实验结果引发的争论。举出两个可能有联系的例子：其一涉及磷酸化对受体的调节作用；其二涉及神经活性药物在病人身上发生的似非而是的效应。本文作者对上述两个问题进行评述。他们认为最近报道的神经递质受体调节和功能与年龄相关的观点，可以解释上述的药物作用。对涉及受体调节功态相互作用（尤其在发育期间）的认识，有可能对神经功能提供新的看法。
In recent years there have been many controversies in the pharmacology literature based on experimental results. Two possible examples are given: one that deals with the regulatory role of phosphorylation on the receptor; and the second, the hypothetical effect that neuroactive drugs have on the patient. The author reviews the above two issues. They think the recently reported neurotransmitter receptor regulatory and function-related perspectives may explain the effects of the drugs described above. Awareness of the involvement of receptors in regulating regulatory interactions, especially during development, may provide new insights into neurological function.