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近年新发现的P6 3和P73蛋白与已知的肿瘤抑制蛋白P5 3在结构和功能上都很相似 ,同属于P5 3蛋白家族。虽然这三种蛋白均具有类似的转录激活和诱导凋亡的活性 ,但是它们在抑制肿瘤的发生及生长发育的调控中各自起着特别的作用
Recently discovered P6 3 and P73 protein and known tumor suppressor protein P5 3 in structure and function are very similar, belong to the P5 3 protein family. Although all three proteins have similar transcriptional and apoptosis-inducing activities, they all play special roles in the inhibition of tumorigenesis and regulation of growth and development