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采用Ｗｉｓｔａｒ大鼠，从怀孕１６天进行限食喂养直到生后４５天，干预组从生后第３６天及第４２天分别给予维生素Ａ灌胃，每次２０００ＩＵ。结果表明，补充维生素Ａ可明显增加大鼠的胸腺重量、肺巨噬细胞的数目、巨噬细胞的吞噬功能及ＮＯ－２的分泌。维生素Ａ可部分纠正营养缺乏导致的免疫缺陷、胸腺萎缩，活化肺巨噬细胞功能，其作用机制有待于进一步研究。
Wistar rats were used for food restriction diet from 16 days of pregnancy until 45 days after birth. The intervention group was administered with vitamin A orally at 361 and 421 days after birth respectively. The results showed that vitamin A supplementation can significantly increase rat thymus weight, the number of pulmonary macrophages, macrophage phagocytosis and NO-2 secretion. Vitamin A can partially correct the immunodeficiency caused by nutritional deficiencies, thymus atrophy, activate the function of pulmonary macrophages, and its mechanism remains to be further studied.