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继发性肝癌的平均生存期因其原发部位的不同而异。继发性肝癌经静脉化疗往往难以奏效,但经肝动脉输往可能有一定疗效。作者对30例仅限于肝转移的病例进行了肝动脉输注短小棒状杆菌(以下简称C.P.)及化疗。输注CP的目的是使肿瘤细胞能与高浓度的免疫治疗剂相接触。本文研究了输注CP的耐受剂量、毒性、及其联合治疗的效果。30个病例应用肝内免疫及化疗的联合疗法共63疗程,52次经股动脉,3次经腋动脉,8次在手术时通过胃十二指肠动脉插入导管。股动脉及腋动脉插管采用Seldinger方法,经皮穿刺选择性动脉插管,通过腹腔动脉插入肝动脉。导管顶端的位置每周检查二次,并保留导管10～12天进行输注。为了减少动脉栓塞可
The average survival time of secondary liver cancer varies depending on the primary site. Intravenous chemotherapy for secondary liver cancer is often ineffective, but transfusion through the hepatic artery may have a certain effect. The authors conducted hepatic arterial infusions of Corynebacterium parvum (C.P.) and chemotherapy in 30 cases that were limited to liver metastases. The purpose of infusion of CP is to allow tumor cells to be contacted with high concentrations of immunotherapeutic agents. This article studies the tolerated dose, toxicity, and the effect of combination therapy of infused CP. In 30 cases, combination therapy with intrahepatic immunization and chemotherapy consisted of 63 courses of treatment, 52 transfemoral arteries, 3 transradial arteries, and 8 intraoperative catheter insertions through the gastroduodenal artery. The Seldinger method was used to intubate the femoral artery and radial artery. The arterial cannula was inserted through the percutaneous puncture and the hepatic artery was inserted through the celiac artery. The position of the tip of the catheter was checked twice a week and catheters were left for 10 to 12 days for infusion. To reduce arterial embolism