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本文从症状轻重不同的病人中分离得A、B、C和D4株阴道毛滴虫,A及B株引起病人产生明显的症状,C株引起的症状较轻,D株系来自无症状的带虫者。将上述4株无菌培养的阴道毛滴虫,经腹腔或皮下接种注入小鼠,结果4株均引起小鼠体内产生脓肿。腹腔注射,以A及D株毒力最强,B及C株次之。皮下注射,A、B两株的毒力大于C、D两株.因此阴道毛滴虫注入小鼠皮下,可以比较不同株对人的致病力的强弱。病理切片结果表明,肝的阴道滴虫性脓肿边缘整齐,外缘有一层阴道毛滴虫密集排列,其长轴与脓肿边缘垂直。与滴虫接触的肝细胞多呈玻璃样变。在脓肿中央有坏死的肝组织及散在的阴道毛滴虫。
In this paper, Trichomonas vaginalis strains A, B, C and D4 were isolated from patients with different severity of symptoms. A and B strains caused obvious symptoms in patients. C strains caused mild symptoms and D strains were from asymptomatic bands Insects. The 4 strains of vaginal Trichomonas vaginalis were inoculated intraperitoneally or subcutaneously into mice, resulting in 4 mice were caused by abscess in vivo. Intraperitoneal injection to A and D strain virulence strongest, B and C strains of the second. Subcutaneous injection, A, B two strains of virulence greater than C, D. Trichomonas vaginalis injected subcutaneously, you can compare the different strains of human virulence. Pathological results showed that the liver vaginal trichomonas abscess edge neat edge of a layer of densely arranged Trichomonas vaginalis, the long axis of the abscess and the vertical edge. Trichomoniasis contact with the liver cells were mostly glassy change. Necrotic liver tissue in the abscess and scattered Trichomonas vaginalis.