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目的探讨原发性高血压患者中,血脂代谢水平与C反应蛋白(CRP)水平的相互关系。方法收集山东大学附属省立医院原发性高血压患者460例,以及健康体检者40例,抽血检测其血脂代谢水平(TC、TG、LDL和HDL水平)以及CRP水平。结果研究发现,和健康对照人群相比,高血压患者整体CRP水平有轻微升高。此外,在高血压患者中,血脂代谢异常组的CRP水平要明显高于血脂代谢正常组,其中LDL和TG水平与CRP水平成明显的正相关,而TC水平与CRP水平关系并不明确。结论研究发现,出现血脂代谢异常的高血压患者其CRP水平会随之升高,而由脂代谢异常所转归的高血压可能与CRP水平升高有一定的关系。
Objective To investigate the relationship between plasma lipid level and C-reactive protein (CRP) levels in patients with essential hypertension. Methods 460 patients with essential hypertension and 40 healthy subjects were collected from Provincial Hospital Affiliated to Shandong University. Blood lipid levels (TC, TG, LDL and HDL levels) and CRP levels were determined by blood sampling. Results The study found that there was a slight increase in overall CRP levels in hypertensive patients compared to healthy controls. In addition, CRP levels in patients with abnormal lipid metabolism were significantly higher than those with normal blood lipid metabolism in patients with hypertension. LDL and TG levels were significantly and positively correlated with CRP levels, while the relationship between TC levels and CRP levels was not clear. Conclusion The study found that patients with hypertensive dyslipidemia CRP levels will rise, while the abnormal lipid metabolism may be associated with elevated levels of CRP may have a certain relationship.