目的:研究六味地黄汤配合耐受性树突状细胞(DC)疫苗联合应用对哮喘小鼠的治疗作用。方法:以六味地黄汤(LW)和/或抗原特异性的耐受性DC疫苗作用于过敏性哮喘小鼠,观察小鼠支气管肺泡灌洗液中嗜酸性粒细胞数目及支气管肺组织病理学改变情况的影响进行研究。结果:本研究成功制备了耐受性DC,并发现六味地黄汤联合耐受性DC在抑制肺炎症细胞浸润尤其是嗜酸性粒细胞方面取得了与注射地塞米松相似的效果,但对减少肺部杯状细胞增生及黏液分泌的作用效果尚不如后者。 Objective: To study the therapeutic effect of Liuwei Dihuang Decoction combined with dendritic cell (DC) vaccine on asthma in mice. Methods: The mice with allergic asthma were treated with LW and / or antigen-specific DC vaccine. The numbers of eosinophils in bronchoalveolar lavage fluid and pathological changes of bronchopulmonary were observed The impact of the situation is studied. Results: This study successfully prepared tolerated DC, and found that Liu Wei Di Huang Decoction combined with tolerated DC in inhibiting lung inflammatory cell infiltration, especially eosinophils with injection of dexamethasone has achieved similar results, but to reduce lung Department of goblet cell proliferation and mucus secretion effect is not as good as the latter.