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采用ELISA法对25例慢性肝炎,105例肝硬化,64例肝癌以及8例急性黄疸型肝炎进行了HBV标志物及抗-HCV的检测.结果:HBV感染率为80.6%,抗-HCV检测阳性率为46%,二者均阳性的双重感染率为32%.其中肝癌组双重感染明显高于肝硬化组P<0.001.单纯抗-HCV检出率为10.8%,说明HBV是引起肝炎、肝硬化、肝癌的主要病因,而HCV感染也是致病因素.对有输血史的慢性肝炎、肝硬化、肝癌100例进行抗-HCV检测,其阳性率59%,而102例无输血史的肝病患者抗-HCV检出率为25%,输血组抗HCV检出率明显高于无输血组P<0.001.其中慢性肝炎、肝硬化、肝癌病人输血组抗-HCV检出率亦明显高于无输血组,各组P<0.001.故提示:HCV感染与输血有密切关系.50例HBV标志物阴性的健康献血员抗-HCV阳性率为6%.
HBV markers and anti-HCV were detected by ELISA in 25 cases of chronic hepatitis, 105 cases of cirrhosis, 64 cases of hepatocellular carcinoma and 8 cases of acute jaundice hepatitis.Results: The HBV infection rate was 80.6%, anti-HCV test was positive Rate of 46%, both were positive for the double infection rate was 32% .In which the double infection of liver cancer group was significantly higher than the cirrhosis group P <0.001. Simple anti-HCV detection rate was 10.8%, indicating that HBV is caused by hepatitis, liver Sclerosis and liver cancer, and HCV infection is also a causative factor.Anti-HCV detection was performed on 100 cases of chronic hepatitis, cirrhosis and liver cancer with a history of blood transfusion, with a positive rate of 59%, while 102 cases of liver disease without blood transfusion history The detection rate of anti-HCV was 25%, the detection rate of anti-HCV in blood transfusion group was significantly higher than that in non-transfusion group (P <0.001), and the detection rate of anti-HCV in blood transfusion group was also significantly higher than that in non-transfusion group Group, P <0.001 in each group, suggesting that HCV infection is closely related to blood transfusion. The positive rate of anti-HCV in 50 HBV-negative healthy blood donors was 6%.