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目的探讨自体角膜缘移植术在局限性或全角膜缘缺陷症治疗中的作用。方法动物实验以兔眼前节碱烧伤制作全角膜缘缺陷症模型，烧伤后实施自体角膜缘移植术治疗。结果动物手术组角膜上皮愈合快，角膜新生血管及炎细胞浸润均轻于对照组。临床研究中所有翼状胬肉均未见复发。结论自体角膜缘移植术治疗角膜缘缺陷症效果显著，是一种符合生理机制的、安全的手术方式。
Objective To investigate the role of limbal autograft in the treatment of focal or full limbal defect. Methods The animal model of corneal limbal defect was made by alkali burn in the anterior segment of rabbit eyes. After the burn, autologous corneal limbal transplantation was performed. Results The animal corneal epithelium healed quickly, corneal neovascularization and inflammatory cell infiltration were lighter than the control group. No recurrence of pterygium was observed in all clinical studies. Conclusion Autologous limbal transplantation for the treatment of limbal defects has a significant effect, is a physiological mechanism in line with the safe operation.