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以氟病区４６名孕妇及其引产胎儿为研究对象，探讨胎儿骨氟水平及骨病理变化与母体氟含量的关系。结果表明：胎儿股骨的平均氟含量为３６８．２μｇ／ｇ．病理改变率为４１．３％；母体尿氟、羊水氟水平与胎儿股骨的氟含量、股骨的病理改变率呈正相关关系；母体有氟斑牙老其胎儿的股骨氟水平及病理改变率明显高于母体无氟斑牙者；胎儿股骨的病理改变率与其自身的氟水平呈剂量反应关系，当骨氟水平大于５０００μｇ／ｇ以上时，改变率达９０％。
Forty-six pregnant women and their fetus fetuses in the fluorosis area were investigated to investigate the relationship between fetal bone fluoride levels and bone pathological changes and the mother’s fluoride content. The results showed that: the average fetal Fetal fluorine content of 368.2μg / g. The rate of pathological changes was 41.3%. There was a positive correlation between fluoride levels in urine and amniotic fluid and fluoride content in fetal femur and histopathological changes in femur. Fetal fluorine level and pathological changes in fetus with dental fluorosis were significantly higher The rate of pathological changes of fetal femur was dose-response relationship with its own fluorine level. When the bone fluorine level was more than 5000μg / g, the rate of change was 90%.