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铜与肝细胞癌(HCC)之间的关系仍有争议,威尔逊氏病(进行性豆状核变性)很少合并肝癌,至今文献中仅见5例 HCC 发生于威尔逊氏病,提示人体内铜积蓄过多对 HCC 有预防作用.Callea 等报道在极少数无肝硬化的 HCC 年轻患者肝癌细胞内含有铜和铜结合蛋白(CBP).本文旨在确定 HCC 与铜贮存的发生频率及其意义,並评价其与 HCC 之间的相互关系。为测定铜和 CBP 的存在,作者收集1980～1984年
The relationship between copper and hepatocellular carcinoma (HCC) remains controversial. Wilson’s disease (progressive somatic degeneration) rarely associates with liver cancer. To date, only 5 HCCs have been reported in Wilson’s disease in the literature, suggesting that copper deposits in the body Too much on the prevention of HCC.Callea et al reported that in a very small number of non-cirrhotic patients with HCC hepatocellular carcinoma containing copper and copper-binding protein (CBP) .This paper aims to determine the occurrence of HCC and copper storage and its significance, and Evaluate its relationship with HCC. To determine the presence of copper and CBP, the authors collected 1980-1984