【摘 要】
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Various boron-containing drugs have been approved for clinical use over the past two de-cades,and more are currently in clinical trials.The increasing interest in boron-containing compounds is due to their unique binding properties to biological targets;f
【机 构】
：
Department of Medicinal Chemistry,Key Laboratory of Chemical Biology,Ministry of Education,School of
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Various boron-containing drugs have been approved for clinical use over the past two de-cades,and more are currently in clinical trials.The increasing interest in boron-containing compounds is due to their unique binding properties to biological targets;for example,boron substitution can be used to modulate biological activity,pharmacokinetic properties,and drug resistance.In this perspective,we aim to comprehensively review the current status of boron compounds in drug discovery,focusing espe-cially on progress from 2015 to December 2020.We classify these compounds into groups showing anti-cancer,antibacterial,antiviral,antiparasitic and other activities,and discuss the biological targets associated with each activity,as well as potential future developments.
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