从胃肠道丢失蛋白质可发生在不少疾病包括粥样泻、局限性肠炎、溃疡性结肠炎、急性胃肠道感染、肠寄生虫病和过敏性胃肠道病变。过去,对不能肯定病因者称之为原发性胃肠道蛋白丢失症,自从1961年Waldmann介绍肠道淋巴管扩张症后,这一名称已被摒弃不用。肠道淋巴管扩张症是一种少见的先天性肠系膜淋巴紊乱性疾病,Walker-Smith报告742例小肠活检中仅发现3例,本文报道的是在新加坡发现的2例中国儿童。例1,7个半月男孩,生后6个月起发现左上肢浮肿并逐渐加重,患儿于出生时即有眼眶浮肿,但无 Loss of protein from the gastrointestinal tract can occur in a number of diseases including atherosclerosis, Crohn’s disease, ulcerative colitis, acute gastrointestinal infections, intestinal parasites and allergic gastrointestinal lesions. In the past, those who could not be sure of the cause were referred to as primary gastrointestinal protein loss disorder, a name that Walgmann had dismissed since 1961 when Waldmann introduced intestinal lymphatic distension. Intestinal lymphangiectasia is a rare congenital mesenteric lymphoid disorder, Walker-Smith reported in 742 cases of intestinal biopsy was found only in 3 cases, this article reports two Singaporean children found in Singapore. For example, one and a half and a half months of age, six months after birth, the left upper extremity edema was found and gradually aggravated. Children had orbital edema at birth but none