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【目的】分析和监测急性肠炎患儿细胞及体液免疫功能的变化。【方法】选取2008年1月至2013年12月本院收治的急性肠炎患儿50例作为观察组,选取同期50例经本院门诊体检显示为健康儿童作为对照组,测定两组儿童的 T 淋巴细胞亚群、血清免疫球蛋白及红细胞免疫功能,并进行比较。【结果】T 淋巴细胞亚群的检测结果比较显示,观察组患儿病发期间 CD3+、CD4+百分率较对照组明显降低(P <0.05)；血清IgG、IgA、IgM 比较显示,观察组患儿病发期间血清 IgG、IgA、IgM 含量均明显低于对照组(P <0.05)；红细胞免疫功能测定结果比较显示,观察组患儿病发期间 RBC-CR1R 明显低于对照组(P 0.05)。【结论】急性肠炎患儿细胞免疫和体液免疫功能发生了明显紊乱,其可能参与了急性肠炎的感染过程；治疗时应维持患儿的免疫功能稳定,以期提高患儿抗感染能力。“,”[Objective]To analyze and monitor the changes of cellular and humoral immune function in children suffering from acute enteritis.[Methods]Totally 50 children with acute enteritis in our hospital from Jan.2008 to Dec.2013 were chosen as the observation group.Meanwhile,50 healthy children by physical ex-amination in clinic service were chosen as the control group.The T-lymphocyte subsets,serum immunoglobu-lin and red blood cell immune function of two groups were measured and compared.[Results]Compared with the control group,the percentages of CD3 + and CD4 + of children in the observation group during the onset were decreased obviously(P <0.05).Serum IgG,IgA and IgM of children in the observation group during the onset were obviously lower than those in control group(P <0.05).The results of red blood cell immune func-tion measurement showed that RBC-CR1R of children in observation group during the onset was obviously lower than that in control group(P 0.05 ).[Conclusion]The cellular and humoral immune function of children with acute enteritis have obvious disorder,which may be involve in the process of acute enteritis infection.The immune function of patients should be maintained during the treatment in order to improve the antiinfection ability of pediatric pa-tients.