自身免疫性肝炎是一不经治疗预后不良的疾病,青年期发病,组织学表现肝硬化或桥接坏死以及检出HLA DR3标志,而不是DR4标志,虽经治疗6～12个月仍不见缓解等是预后不良的标志。 免疫抑制治疗可使病人的存活期延长。重要的 Autoimmune hepatitis is an untreated disease with poor prognosis. Adolescent onset, histologic findings of cirrhosis or bridging necrosis, and detection of the HLA DR3 marker, not the DR4 marker, have not been alleviated, etc., even after 6 to 12 months of treatment Is a sign of poor prognosis. Immunosuppressive therapy prolongs the patient’s survival. important