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目的探讨单纯化疗对尤文肉瘤术后脑、肺多发转移的治疗效果。方法回顾分析2013年1月收治的1例尤文肉瘤术后患者的临床资料。男性,25岁。2011年4月于我院确诊为左股骨上段尤文肉瘤,按VAC+IE方案化疗1个疗程后,行瘤段切除,肿瘤假体置换。术后病人未按医嘱要求进行化疗,2a后出现脑、肺转移。再次按照VAC+IE方案化疗。结果再次化疗1个疗程后,病人头痛症状明显缓解。肺部X线片示治疗后肺野内占位消失。头颅CT平扫示化疗后脑实质转移灶较化疗前显著缩小,脑室系统对称。结论 VAC+IE化疗方案对尤文肉瘤脑、肺多发转移的治疗有效。
Objective To investigate the curative effect of chemotherapy alone on the brain and lung metastasis after Ewing sarcoma. Methods The clinical data of one patient with Ewing sarcoma admitted in January 2013 were retrospectively analyzed. Male, 25 years old. In April 2011 in our hospital diagnosed as left femur Ewing sarcoma, according to VAC + IE regimen after a course of chemotherapy, tumor resection, replacement of tumor prosthesis. After the patient did not follow the doctor’s instructions for chemotherapy, 2a after brain and lung metastases. Again according to VAC + IE program chemotherapy. The results of a course of chemotherapy after chemotherapy, the patient’s headache symptoms were significantly alleviated. Pulmonary X-ray showed disappearance of occupancy in the lung field after treatment. Skull CT scan showed that after chemotherapy, the parenchyma metastasis was significantly reduced compared with that before chemotherapy, and the ventricular system was symmetrical. Conclusion The VAC + IE chemotherapy regimen is effective in the treatment of Ewing’s sarcoma with multiple brain metastases.