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目的分析外周血管阻力异常者在正常人群中的分布及相关因素的影响。方法采用Bioz.com数字化无创血液动力学监护仪,检测1695名正常健康人外周血管阻力(SVR)及收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、心率(HR)、心输出量(CO)、心指数(CI)、搏出量(SV)、搏出指数(SI)、左心做功量(LCW)等循环功能参数,并进行了相关因素分析。结果外周血管阻力异常发生率在10～12岁最高,16～18岁降至最低;之后随年龄增长而增加;男、女性之间差异无统计学意义。相关因素分析显示,SVR与年龄(Age)、SBP、DBP、MAP呈正相关;而与HR、CO、CI、SV、SI、LCW呈负相关。其中CO和MAP具有独立显著性影响,SVR异常可导致CO下降、血压升高。结论外周血管阻力升高与年龄、CO及血压水平密切相关,其可能是早期动脉血管结构和功能损害的结果和标志。
Objective To analyze the distribution of peripheral vascular resistance in normal population and the influence of related factors. Methods Using Bioz.com digital noninvasive hemodynamic monitor, peripheral vascular resistance (SVR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR) Cardiac output (CO), cardiac index (CI), stroke volume (SV), stroke index (SI) and left ventricular work volume (LCW) were measured and related parameters were analyzed. Results The incidence of abnormal peripheral vascular resistance was the highest in 10 ~ 12 years and the lowest in 16 ~ 18 years, then increased with the increase of age. There was no significant difference between male and female. Correlation analysis showed that SVR was positively correlated with age, SBP, DBP and MAP, but negatively correlated with HR, CO, CI, SV, SI and LCW. Among them, CO and MAP had independently significant effects. Abnormal SVR could lead to the decrease of CO and the increase of blood pressure. Conclusion The increase of peripheral vascular resistance is closely related to age, CO and blood pressure level, which may be the result and sign of the early damage of arterial structure and function.