蝙蝠葛碱对异丙肾上腺素量—效反应的影响与戊脉安和粉防己碱相似,不同于β-受体竞争性拮抗剂心得安。对Ca~(2+)量—效反应的影响,亦与戊脉安和粉防己碱相似,表现为竞争性和非竞争性双重拮抗作用。在对猫乳头肌电—机械活动影响方面,对SEG的影响类似奎尼丁:R波降低,增宽,R-T延长;但同时显著抑制收缩力。结果说明蝙蝠葛碱可能具有“钙拮抗剂样”抗Ca~(2+)作用和“奎尼丁样’抑制Na~+内流的作用。 The effect of dauricine on the amount-response of isoproterenol is similar to that of verapamil and tetrandrine, unlike diazepam, a beta-receptor antagonist. Ca ~ (2+) dose-response effect, but also with verapamil and tetrandrine similar to the performance of the competitive and non-competitive dual antagonism. The effect on SEG was similar to that of quinidine in the effect on electromechanical activity of the papillary muscles of the cats: R wave reduction, broadening, R-T prolongation; but significant inhibition of contractility at the same time. The results indicate that dauricine may have “calcium antagonist” anti-Ca 2+ effect and “quinidine-like” inhibit Na ~ + influx.