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目的:观察自体疣皮下埋植联合微波治疗妊娠中期尖锐湿疣(CA)的疗效。方法:将该院2005年6月～2008年6月65例CA患者随机分为两组,观察组32例行自体疣皮下埋植联合微波治疗;对照组33例单行微波治疗。术后每2周复查1次,随访6个月。结果:治疗后3～4天,局部CA结痂自行脱落,创面一般于7天愈合。观察组治愈27例,治愈率84.38%;对照组治愈18例,治愈率54.55%;两组疗效比较差异有统计学意义(P<0.05)。治疗后第1周两组复发率比较差异无统计学意义(P>0.05),治疗第4周、12周、24周两组复发率比较观察组均低于对照组,差异有统计学意义(P<0.05及P<0.01)。两组病例中有7例经阴道分娩,58例剖宫产。两组均未出现影响治疗效果的不良反应。结论:自体疣皮下埋植联合微波是治疗妊娠期CA的有效方法。
Objective: To observe the curative effect of autogenous wart implanted with microwave in the treatment of second trimester condyloma acuminatum (CA). Methods: Sixty-five patients with CA in our hospital from June 2005 to June 2008 were randomly divided into two groups. In the observation group, 32 cases were treated with autologous wart implanted with microwave and 33 cases in the control group treated with microwave alone. After every 2 weeks review 1, followed up for 6 months. Results: 3 to 4 days after treatment, local CA scab off itself, wound healing in 7 days. In the observation group, 27 cases were cured, the cure rate was 84.38%. In the control group, 18 cases were cured, the cure rate was 54.55%. The difference between the two groups was statistically significant (P <0.05). There was no significant difference in relapse rate between the two groups at the first week after treatment (P> 0.05). The relapse rate of the two groups at the 4th week, 12th week and 24th week after treatment was lower than that of the control group (P <0.05), the difference was statistically significant P <0.05 and P <0.01). Seven patients in the two groups had vaginal delivery and 58 had cesarean delivery. No adverse effects were found in both groups. CONCLUSION: Subcutaneous implantation combined with microwave is an effective method for the treatment of gestational CA.