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对来自孟加拉、泰国、印度、中国四地区Ｏ１３９型霍乱菌株进行了毒力、免疫原性、免疫力与相互交叉保护力试验，结果显示不同地区分离的Ｏ１３９型霍乱弧菌其所试特性相互间无差异。用中国（９３－３）株试制的菌体菌苗，其抗原性、毒性、免疫力安全性等经检定符合霍乱菌苗规程要求。鉴于Ｏ１３９型霍乱弧菌存在荚膜的特性，而现有的几种荚膜多糖菌苗都显示有明显的保护作用，因而，使用Ｏ１３９型菌苗有可能在一定程度上达到控制Ｏ１３９型霍乱流行的目的。
The virulence, immunogenicity, immunity and cross-protection of O139 cholera strains from Bangladesh, Thailand, India and China were tested. The results showed that the characteristics of V. cholerae O139 isolated from different regions were different from each other No difference. With China (93-3) strains of bacterial strains of bacteria trial, its antigenicity, toxicity, immunity and other safety tests in line with the requirements of cholera vaccine regulations. Given the capsular nature of Vibrio cholerae O139, several existing capsular polysaccharide vaccines have shown significant protective effects, it is possible to use O139-type vaccine to some extent to control the prevalence of cholera O139 the goal of.