应用微核试验、Ames 试验和原噬菌体诱导方法检测了毒黄素的致突变性。试验结果显示,毒黄素的浓度在2.8mg/kg 和1.4mg/kg 时,微核试验阴性。浓度为382μg/皿、38.2μg/皿和0.38μg/皿时,Ames 试验阴性。在382μg/ml、191μg/ml 和95μg/ml 时,对溶原性细菌无诱导能力,但有抑菌作用。 Micronucleus test, Ames test and prophage induction method were used to detect the mutagenicity of toxin. The test results showed that the micronucleus test was negative when the concentration of the toxin was 2.8 mg / kg and 1.4 mg / kg. The Ames test was negative at concentrations of 382 μg / dish, 38.2 μg / dish and 0.38 μg / dish. At 382μg / ml, 191μg / ml and 95μg / ml, no induction of lysogenic bacteria, but antibacterial effect.