论文部分内容阅读
目的观察多索茶碱对老年肺功能下降患者的临床疗效。方法将134例肺功能下降的老年患者随机分为观察组和对照组各67例。在常规内科治疗的基础上,观察组加用多索茶碱治疗,对照组给予氨茶碱治疗,比较2组的治疗效果和不良反应发生情况。结果观察组治疗总有效率为89.55%高于对照组的67.16%,差异有统计学意义(P<0.05)。治疗前2组各项肺功能指标差异均无统计学意义(P>0.05);2组治疗后各项肺功能指标均较治疗前显著升高,且观察组升高幅度大于对照组,差异均有统计学意义(P<0.05)。2组患者治疗后血气分析各指标均较治疗前有所改善(P<0.05),且观察组治疗后PCO2低于对照组,PO2、Sa O2高于对照组(P<0.05);观察组不良反应发生率低于对照组,差异有统计学意义(P<0.01)。结论多索茶碱治疗老年肺功能下降效果较好,不良发生发生率较低,安全性较好。
Objective To observe the clinical efficacy of doxofylline in elderly patients with pulmonary function decline. Methods A total of 134 elderly patients with decreased lung function were randomly divided into observation group (67 cases) and control group (67 cases). On the basis of routine medical treatment, the observation group was treated with doxofylline, the control group was treated with aminophylline, and the treatment effect and adverse reactions in the two groups were compared. Results The total effective rate of observation group was 89.55% higher than 67.16% of control group, the difference was statistically significant (P <0.05). There was no significant difference in the indexes of pulmonary function between the two groups before treatment (P> 0.05). The indexes of pulmonary function in the two groups after treatment were significantly higher than those before treatment, and the increase in the observation group was greater than that in the control group There was statistical significance (P <0.05). After treatment, the blood gas analysis indexes in both groups were improved (P <0.05), and the PCO2 in the observation group was lower than that in the control group (P <0.05); the levels of PO2 and SaO2 were higher in the observation group than those in the control group The incidence of the reaction was lower than that of the control group, the difference was statistically significant (P <0.01). Conclusion Doxofylline treatment of elderly lung function better, less incidence of adverse reactions, safety is better.