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慢性肾小球肾炎是外源植入性抗原和内源自身性抗原所致的机体免疫功能失调。已有报告证明,某些病毒,如肝炎病毒、流感 A_2病毒可能是造成肾炎的外源性抗原。本文检测了45例慢性肾炎病人血清中柯萨奇B 组(CoxB 组)病毒的特异性 IgM,试图对 CoxB 组病毒感染与肾炎发病的关系进行探讨。对象和方法一、对象:45例慢性肾小球肾炎,均为活动期,男19例,女26例,年龄21～55岁,平均37.1岁,均为本科住院病人。正常对照组30例,均为健康献血员。
Chronic glomerulonephritis is an exogenous implantable antigen and endogenous own antigens caused by immune dysfunction. It has been reported that certain viruses, such as hepatitis virus and influenza A_2 virus, may be exogenous antigens causing nephritis. In this paper, 45 patients with chronic nephritis serum Coxsackie B (CoxB group) virus-specific IgM, trying to CoxB group of viral infection and the incidence of nephritis were explored. Subjects and methods First, the object: 45 cases of chronic glomerulonephritis, are active, 19 males and 26 females, aged 21 to 55 years, mean 37.1 years, are undergraduate inpatients. Normal control group of 30 patients, all healthy blood donors.