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目的左甲状腺素替代治疗对绝经后亚临床甲减患者心室结构和功能的影响。方法选择本院2015年4月-2016年9月收治绝经后亚临床甲减患者142例,随机分成观察组和对照组,各组71例;对照组亚临床甲减患者采用常规治疗,观察组患者应用左甲状腺素替代治疗。对比2组亚临床甲减患者各项指标情况。结果观察组亚临床甲减患者左心室功能各指标情况均优于对照组(P<0.05);观察组患者甲状腺功能各指标均优于对照组(P<0.05)。结论采用左甲状腺素替代治疗能有效改善患者心室功能,促使亚临床甲减患者甲状腺功能恢复正常。
Objective To investigate the effect of levothyroxine replacement therapy on ventricular structure and function in postmenopausal subclinical hypothyroidism. Methods Select 142 cases of sub-clinical hypothyroidism in our hospital from April 2015 to September 2016 were randomly divided into observation group and control group, with 71 cases in each group. The control group was treated with conventional therapy and the observation group Patients with levothyroxine replacement therapy. Comparison of two groups of subclinical hypothyroidism in various indicators of the situation. Results All the indexes of left ventricular function in subclinical hypothyroidism group were better than those in control group (P <0.05). The indexes of thyroid function in observation group were better than those in control group (P <0.05). Conclusions Levothyroxine replacement therapy can effectively improve the ventricular function in patients with subclinical hypothyroidism to promote thyroid function returned to normal.