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选用Ｌ＿（１２）（２￣（１１））正交表，通过薄层扫描法，测定补骨脂素、异补骨脂素的含量，研究温补肾阳方中各药与补骨脂的配伍变化。结果显示，调配处方时，将补骨脂捣碎使用，可显著增加有效成分的煎出，温补肾阳方的补骨脂与健脾药大枣、黄芪合用，可显著提高补骨脂有效成分的煎出，白芍、丹参、当归、菟丝子可显著增加有效成分的煎出，而制首乌、熟地具有降低有效成分煎出的趋势。实验结果揭示中医方药“相使”配伍的内在物质基础。
The L_(12)(2~(11)) orthogonal table was used to determine the content of psoralen and isopsoralen by thin-layer scanning to study the compatibility of each of the drugs in the Bushen Shenyang Decoction with psoralen. Variety. The results showed that when the prescription was dispensed, the psoralen was used to break up, which significantly increased the frying of the active ingredients. The combination of Wenshen Yangfang’s psoralen and the spleen-enhancing drugs, jujube and Huangqi, can significantly increase the effective components of psoralen. The fried, white peony root, salvia miltiorrhiza, angelica, and dodder seed can significantly increase the decoction of the active ingredient, while the system of Shouwu and Rehmannia has the tendency of reducing the effective ingredient to decoct. The experimental results reveal the internal material basis of compatibility of traditional Chinese medicine prescriptions.