奎尼丁(Quinidine)是奎宁的一种右旋异构体,从1914年始已用于治疗心律不齐,诸如对期前收缩、心动过速、心房纤颤和心房扑动等均有疗效。其作用为减少传导速率及降低应激性。由于心脏病患者平均年龄的增加与寿命的延长,被奎宁丁治疗的病人大增。虽然这种药物引起的急性血小板减少曾有报导,但在口腔科文献中仅发现有两例。报导本病例的目的在于强调奎尼丁引起血小板减少在口腔科的重要性,因为病人的早期主诉多为口腔出血。 Quinidine is a dextrorotatory isomer of quinine and has been used to treat arrhythmias since 1914, such as efficacy in pre-systolic, tachycardia, atrial fibrillation and atrial flutter. . Its role is to reduce the conduction rate and reduce stress. Because of the increase in the average age of heart disease patients and the extension of their lives, the number of patients treated with quinidine increased significantly. Although there have been reports of acute thrombocytopenia induced by this drug, only two cases were found in the dental literature. The purpose of this case was to emphasize the importance of quinidine-induced thrombocytopenia in dentistry because the patient’s early complaints were mostly oral bleeding.