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目的比较阿奇霉素与培氟沙星治疗小儿急性肠胃炎的效果。方法 76例急性肠炎患儿,按照随机方式分为对照组和治疗组,各38例。治疗组患儿采用阿奇霉素予以治疗,对照组患儿采用培氟沙星予以治疗,对比两组患儿不良反应情况及治疗效果。结果经4 d治疗后,治疗组患儿总有效率为97.37%,对照组为78.95%,治疗组总有效率明显优于对照组(P<0.05);治疗4 d后,治疗组出现轻度腹痛及恶心等不良反应2例(5.26%);对照组出现轻度腹痛及恶心等不良反应4例(10.53%),比较差异无统计学意义(P>0.05)。结论针对小儿急性肠胃炎,采用阿奇霉素与培氟沙星相比具有更为显著的治疗效果,且不良反应少,可在临床应用。
Objective To compare the effect of azithromycin and pefloxacin on children with acute gastroenteritis. Methods 76 children with acute enteritis were randomly divided into control group and treatment group, with 38 cases in each. The treatment group was treated with azithromycin, and the control group was treated with pefloxacin. The adverse reaction and the treatment effect were compared between the two groups. Results After 4 days of treatment, the total effective rate was 97.37% in the treatment group and 78.95% in the control group, and the total effective rate in the treatment group was significantly better than that in the control group (P <0.05). After 4 days of treatment, the treatment group showed mild Two cases (5.26%) had adverse reactions such as abdominal pain and nausea. There were 4 adverse reactions (10.53%) in the control group, including mild abdominal pain and nausea. There was no significant difference between the two groups (P> 0.05). Conclusion Acute gastroenteritis in children with azithromycin and pefloxacin compared with more significant therapeutic effect, and fewer adverse reactions, can be used clinically.