盐酸甲胺苯脒*(Amidantel),化学名为N-{4-[1-(二甲氨基)乙叉基]氨基}苯基-2-甲氧乙酰胺盐酸盐,1971年由Wollweber等合成。国外动物试验结果~[1,2]:对驱犬体内的犬钩虫、狭头钩虫、弓蛔虫和狮弓蛔虫有显著效果,对鼠钩虫、鼠类园线虫、棉鼠丝虫和未氏盖头丝虫亦有作用;毒性低,未显示致畸胎性和致突变性。国外临床初试结果~[1,3]:对驱人体十二指肠钩虫、美洲钩虫和蛔虫均有疗效。 Amidantel hydrochloride, chemical name N- {4- [l- (dimethylamino) ethylidene] amino} phenyl-2-methoxyacetamide hydrochloride, 1971 by Wollweber et al synthesis. Foreign animal test results ~ [1,2]: the canine dogs in vivo dogs hookworm, narrow-necked hookworm, roundworm and lion bow roundworm have significant effect on the hookworm, rodent Parkinson’s disease, cotton wireworm and non- Filarial also has a role; low toxicity, did not show teratogenic and mutagenicity. Foreign clinical trial results ~ [1,3]: to drive the human body duodenal hookworm, hookworms and roundworms are effective.