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目的总结无功能胰岛细胞瘤的外科诊治经验。方法回顾性分析24例无功能胰岛细胞瘤的临床资料。结果本组以腹部包块、腹痛、腹胀为主要首发症状。病灶主要位于胰头(62.5%)和胰尾部(20.8%)。2例为多发,均位于胰头。恶性肿瘤占45.8%,良性占54.2%,肿瘤最大径平均为6.5cm。胰体尾切除和胰十二指肠切除各占20.8%,单纯肿瘤切除占58.4%。术后主要并发症为胰瘘(16.7%)和腹腔出血(8.3%),均发生在单纯肿瘤切除的病例。良性肿瘤组中位生存期36.68个月,恶性肿瘤组的中位生存期15.67个月。结论无功能胰岛细胞瘤无特异症状;单纯肿瘤切除并发症发生率高,需行肿瘤所在部位的胰腺区域切除。
Objective To summarize the experience of surgical diagnosis and treatment of non-functional islet cell tumor. Methods Retrospective analysis of 24 cases of non-functional islet cell tumor clinical data. Results The group of abdominal mass, abdominal pain, abdominal distension as the main first symptom. The lesions were mainly located in the head of the pancreas (62.5%) and the tail of the pancreas (20.8%). 2 cases of multiple, are located in the head of the pancreas. Malignant tumors accounted for 45.8%, benign tumors accounted for 54.2%, the average diameter of the tumor was 6.5cm. Pancreatic resection and pancreatoduodenectomy accounted for 20.8%, simple tumor resection accounted for 58.4%. The main postoperative complications were pancreatic fistula (16.7%) and peritoneal hemorrhage (8.3%), all of which occurred in cases of simple tumor resection. The median survival time was 36.68 months in the benign tumor group and 15.67 months in the malignant tumor group. Conclusion There is no specific symptom of non-functioning islet cell tumor. The incidence of simple tumor resection complication is high, and it is necessary to excise the pancreas area where the tumor is located.