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测试了启东肿瘤病人、配偶及其子女的氮一乙酰化转移酶多态表型,计算了各组的基因频率,分析了慢型的优势比,慢型者的肝癌危险度6.87倍为最著。配偶的氮一乙酰化转移酶多态型的分布如常。患者子女的慢型比例也较高,他们的基因频率(0.56左右)与理论预期值相同。氮一乙酰化酶多态的遗传规律符合常染色体隐性遗传。
The polymorphic phenotypes of nitrogen-acetyltransferases in Qidong cancer patients, their spouses and their children were tested. The frequency of genes in each group was calculated and the odds ratio of the slow type was calculated. The risk of liver cancer in the slow type was 6.87 times. Most famous. The distribution of the nitrogen-acetyltransferase polymorphism of the partner is as usual. The proportion of patients with the slow type of patients is also higher, and their gene frequency (around 0.56) is the same as the theoretical expected value. The inheritance pattern of nitrogen-acetylase polymorphism is consistent with autosomal recessive inheritance.