粘多糖病Ⅱ型临床极为少见，笔者遇1例现报道如下。1病例报告患儿，男，11岁，因憋气、不思饮食5天于1997年8月12日入院。患儿系第一胎第一产，足月顺产，出生时无窒息及宫内窘迫、产伤等，出生后至3岁前发育基本正常，四肢活动及语言功能同同龄儿。4岁后患儿逐渐出现听力障碍 Mucopolysaccharidosis type II clinical extremely rare, I met the case is reported as follows. 1 case report Children, male, 11 years old, due to suffocation, do not think diet 5 days in August 12, 1997 admission. Children with first birth of the first birth, term full-term, at birth without asphyxia and intrauterine distress, birth trauma, etc., after birth to 3 years old basically normal development, limb activity and language function with the same age children. 4 years after the children gradually hearing loss