代谢综合征是一组复杂的代谢紊乱症候群,包括胰岛素抵抗、血脂障碍、高血压和肥胖等病理变化。发病机制尚未完全明确,已证明炎症在其发生、发展和预防中有重要作用。硫化氢属内源性气体信号分子家族,近年来,越来越多的证据表明内源性硫化氢的代谢异常与多种疾病相关。本文就代谢综合征、炎症、硫化氢之间的关系予以综述。 Metabolic syndrome is a complex group of metabolic disorders, including pathological changes such as insulin resistance, dyslipidemia, hypertension and obesity. The pathogenesis is not yet completely clear, inflammation has been proved in its occurrence, development and prevention have an important role. Hydrogen sulfide is a family of endogenous gas signaling molecules. In recent years, more and more evidences indicate that the abnormal metabolism of endogenous hydrogen sulfide is associated with various diseases. This article reviews the relationship between metabolic syndrome, inflammation, and hydrogen sulfide.