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目的探讨红细胞分布宽度(RDW)、平均血小板体积(MPV)和血清白蛋白(ALB)、球蛋白(GLB)水平与急性脑梗死的关系。方法通过比较148例急性脑梗死患者与148例体检健康者的血红细胞、血小板参数和血清蛋白水平,探讨其与急性脑梗死的关系。结果急性脑梗死组RDW、MPV、血小板分布宽度(PDW)、GLB水平明显高于对照组(P<0.01),ALB水平、白蛋白/球蛋白比率(A/B)明显低于对照组(P<0.01),logistic回归分析显示RDW、MPV、GLB的升高和ALB的降低与急性脑梗死独立相关。结论 RDW、MPV、GLB的升高和ALB水平的降低可能是急性脑梗死的独立危险因素。
Objective To investigate the relationship between RDW, MPV, ALB, GLB and acute cerebral infarction. Methods Erythrocyte, platelet parameters and serum protein levels in 148 patients with acute cerebral infarction and 148 healthy controls were compared to explore their relationship with acute cerebral infarction. Results The levels of RDW, MPV, PDW and GLB in acute cerebral infarction group were significantly higher than those in control group (P <0.01), ALB level and albumin / globulin ratio (A / B) were significantly lower than those in control group <0.01). Logistic regression analysis showed that elevated RDW, MPV, GLB and ALB decreased independently of acute cerebral infarction. Conclusions The elevation of RDW, MPV, GLB and the decrease of ALB level may be independent risk factors for acute cerebral infarction.