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目的探讨尿微量白蛋白(mALB)联合胱抑素C(CysC)检测在糖尿病早期肾损伤中的临床应用价值。方法采用免疫比浊法对83例不同程度的糖尿病患者进行胱抑素C联合尿微量白蛋白检测,结果与60例健康体检者结果对比分析。结果 83例糖尿病患者中胱抑素C的阳性率为42.2%,尿微量白蛋白的阳性率为39.8%。两项联合检测的阳性率为54.2%。结论胱抑素C联合尿微量白蛋白检测对糖尿病早期肾损伤的诊断有重要参考价值,两项联合检测可提高诊断灵敏度。
Objective To investigate the clinical value of urine microalbumin (mALB) combined with cystatin C (CysC) detection in the early stage of diabetic nephropathy. Methods Immunocytochemistry was used to detect cystatin C and urine microalbumin in 83 patients with different degrees of diabetes. The results were compared with those of 60 healthy subjects. Results The positive rate of cystatin C in 83 diabetic patients was 42.2% and the positive rate of urine microalbumin was 39.8%. The positive rate of the two combined tests was 54.2%. Conclusion The combination of cystatin C and urine microalbumin has important reference value for the diagnosis of early diabetic nephropathy. The two combined tests can improve the diagnostic sensitivity.